19th Ave New York, NY 95822, USA

FINAL PROGRAM & ABSTRACTS

Glasgow local time

Thursday, June 23rd

09:00 – 09:15            Connection

09:15 – 09:30            Welcome Remarks   

                                        Rhian Touyz (Glasgow, UK – Montreal, Canada)

                                         Federica I Wolf (Rome, Italy)                    

 

09.30 – 11:40               SESSION 1 Magnesium: Environment, Nutrition and Health

Chairmen:                    Andrzej Mazur (Clermont-Ferrand, France)

                                           Rhian Touyz (Glasgow, UK – Montreal, Canada)

 09:30 – 09:50                Hypomagnesaemia: biomarker, relevance, clinical implications

                                             Andrea Rosanoff

                                             CMER Center for Magnesium Education and Research, Pahoa, USA

 09:50 – 10:10                Magnesium in soil and consequences in the food chain 

                                             Roberta Cazzola

                                             Department of Biomedical and Clinical Sciences, University of Milano, Italy

10:10 – 10:30                Magnesium: one of the building block of life

                                           Stefano Iotti

                                           Department   of  Pharmacy   and  Biotechnology,  University of Bologna, Italy  

 10:30 – 10:45                Coffee / Tea Break

10:45 – 11:05                Cyclin M4 silencing and magnesium accumulation in NASH

                                            Maria Luz Martinez-Chantar

                                         Laboratory of Head, Liver DiseaseSpanish Carlos III Health Institute, Derio, Spain

11:05 – 11:25                Magnesium and Thiamine in Alcohol Withdrawal Syndrome

                                            Donogh Maguire

                                            Glasgow Royal Infirmary, University of Glasgow, UK

 11:25 – 11:40                General Discussion

11:40 – 12:25                Oral Communications

11:40 – 11:55                OC01

                                           Mg quantification and distribution as  potential biomarkers in Colorectal Cancer

                                          Agnese Razzoli

                                        Department of Transfusion Medicine, University of Reggio Emilia,  Italy

11:55 – 12:10             OC02

                                        Magnesium alleviates moderate stress in fibromyalgia

                                       Nicolas Macian

                                      Department of Clinical Investigation, INSERM Clermont-Ferrand, France

12:10 – 12:25                OC03

                                           Decreased ionized magnesium and an increased ionized calcium/magnesium ratio in elderly hypertensives — relationship to artheriosclerosis

                                          Klaus Kisters

                                          Department of Med. Klinik, St. Anna Hospital & ESH Excellence Centre, Herne, Ruhr University Bochum, Germany

 12:25 – 13:30              Lunch Break

 13:30 – 13:50            Keynote Lecture   

                                        Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism

                                        Muniswamy Madesh

                                       Department of Medicine, University of Texas Health, San Antonio, USA

 13:50 – 13:55          Discussion

13:55 – 14:15           Magnesium, immunity and infectious diseases an updated overview

                                      Michael Lenardo

                                      Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Besthesda, USA

14:15 – 14:20          Discussion

 14:20 – 16:00         SESSION 2    Magnesium through the lifespan   

Chairmen:                Ka Kahe (New York, USA)

                                       Federica I Wolf (Roma, Italy)

 14:20 – 14:40        Mg and development

                                    Loren Runnels

                                    Department of Pharmacology Rutgers, Robert Wood Johnson Medical School

Piscataway, NJ, USA

 14:40 – 15:00      Mg and aging

                                   Ligia Dominguez

                                   Department of Medicine and Surgery, Kore University of Enna, Italy

 15:00 – 15:20     Magnesium and Progeria

                                 Ricardo Villa-Bellosta

                                Department of Biochemistry and Molecular Biology, University of Santiago de Compostela, Spain 

 15:20 – 15:40    Magnesium, an invisible deficiency that could be harming your muscle health

                                Sara Castiglioni

                               Department of Clinical and Biomedical Sciences “Luigi Sacco”, University of Milano, Italy

15:40  – 15:50    General discussion                

15:50  – 16:00     Coffee / Tea Break

16:00  –  16:45    Oral Communications

16:00  –  16:15     OC04

                                  Can a Qualified Health Claim for Magnesium and High Blood Pressure Advance Public Health?  

                                 Rebecca Costello and Andrea Rosanoff

                                 CMER Center for Magnesium Education and Research, Pahoa, USA

16:15 – 16:30          OC05

                                    Fluorescent Indicators for Detection of Cellular Mg2+ with High Selectivity

                                   Daniela Buccella

                                  Department of Chemistry, New York University, New York, USA

16:30 – 16:45      OC06

                                 Magnesium effect on the cardiovascular-muscle-bone triad

                                 Marie-Eva Pickering

                                 Department of Rheumatology, University Hospital Clermont-Ferrand, France

16:45 – 17:00    OC07

                                Lactobacillus fermentum supplementation normalizes magnesium fecal excretion and delays and reduces high blood pressure and                                  Na, Na/K ATPase activities in salt dependent hypertension

                                Ruben Biomon

                                Department of Biophysics and Biochemistry, Venezuelan Institute of Scientific Research, Miranda State, Venezuela

Friday, June 24th

09:00 – 11:00        SESSION 3

                                    Molecular Mechanisms of Magnesium Homeostasis

Chairmen:             Francisco Rios (Glasgow, UK)                                            Jeroen de Baaji (Nijmegen, The Netherlands)

 09:00 – 09:20       The molecular appearance and regulatory mechanisms of TRPM7 channel complexes

                                    Vladimir Chubanov

                                     Department of Pharmacology and Toxicology, Walther-Straub Institute, LMU Munich, Germany

09:20 – 09:40        Genetic and drug-induced hypomagnesemia: different cause, same mechanism

                                   Jeroen De Baaij

                                  Department of Molecular Life Sciences, Radboud Institute, Nijmegen, the Netherlands

 09:40 – 10:00     Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family

                                 Cristina Manatschal

                                  Department of Biochemistry, University of Zurich, Switzerland

 10:00 – 10:10    Coffee / Tea Break

10:10 – 10:30     Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis

                                Francisco Rios

                                 Department of Cardiovascular and Medical Sciences, University of Glasgow, UK

10:30 – 10:50     Severe magnesium wasting in Kenny Caffey Syndrome- searching for molecular causes

                                Heidi Schigt

                               Department of Molecular Life Sciences, Radboud Institute, Nijmegen, the Netherlands

                                Francisco Rios

                                 Department of Cardiovascular and Medical Sciences, University of Glasgow, UK

10:50 – 11:00  General Discussion  

11:00 – 12:00   Oral  Communications

 11:00 – 11:15  OC08

                               Palmitoylation regulates cellular distribution of and transmembrane Calcium flux through TrpM7                    

                               Xing GAO

                               Department of Cardiovascular & Medical Sciences, University of Glasgow, UK

11:15 – 11:30  OC09

                              TRPM7 Modulates Human Pancreatic Stellate Cell Activation

                             Julie Auwercx

                             Department of Sciences, University of Picardie Jules Verne, Amiens, France

11:30 – 11:45   OC10

                              TRPM7 channel-kinase, magnesium and pH in immune cells

                              Ashot Kozak

                             Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine, Wright State University, Dayton, USA

11:45 – 12:00  OC11

                              TRPM7 kinase mediates hypomagnesemia-associated seizure and death

                              Samuel Dudley

                              Department of Medicine, Division of Cardiology, the Lillehei Heart Institute, University of Minnesota at Twin Cities, Minneapolis, USA

12:00 – 13:00   Lunch Break

13:00 – 15:00   SESSION 4

                              Magnesium in communicable disease

Chairmen:        Federica I Wolf (Roma, Italy)

                              Jeanette AM Maier (Milano, Italy)

13:00 – 13:20 How Pathogens Feel and Overcome Magnesium Limitation

                              Eduardo A. Groisman
                              Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, USA

13:20 – 13:40   Counteract bacterial infections: factor SLC11A1 restricts Salmonella growth through magnesium deprivation

                              Olivier Cunrath

                              Department of Metals and Microorganisms, University of Strasbourg, Illkirch, France

13:40 – 14:00  Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation

                             Asparouh Iliev

                             Department of Molecular Neuroinfectiology, University of Bern, Switzerland

14:00 – 14:20 The PRL-2:CNNM protein complex and magnesium interaction in the modulation of adenoviral infection

                              Michel L. Tremblay

                               Department of Biochemistry and Goodman Cancer Institute. McGill University, Montreal, Canada

14:20 – 14:40   Mg in Sars-Cov-2

                               Fernando Guerrero-Romero

                              Biomedical Research Unit of the Mexican Social Security Institute at Durango,  Research Group on Diabetes and Chronic Illnesses at Durango, Mexico

14:40 – 15:00    Increased Mortality Associated with Hypermagnesemia in Severe COVID-19 Illness

                                Jacob Stevens

                                Department of Nephrology, Columbia University Irving Medical Center New York, USA     

15:00 – 15:10             General Discussion                         

15:10 – 15:25  Oral Communication

                               OC12

                               Use of Magnesium for Preventing Cardiac Damages by SARS-CoV-2

                               Jin O-Uchi

                               Department of Medicine University of Minnesota, USA

15:25 – 15:30  Coffee / Tea Break

15:30 – 16:40   SESSION 5      

                              Magnesium in noncommunicable diseases

Chairmen:      Oliver Micke (Bielefeld, Germany)

                             Rhian Touyz (Glasgow, UK – Montreal, Canada)

15:30 – 15:50  Serum magnesium concentration and incident cognitive impairment: findings from the REGARDS study

                             Ka Kahe

                             Columbia University Irving Medical Center, New York, USA

15:50 – 16:10 Magnesium in oncology an update

                            Oliver Micke

                           Department of Radiotherapy and Radiation Oncology, Franziskus Hospital

Bielefeld, Germany

16:10 – 16:30 News on Magnesium and the Vascular system

                            Jeanette AM Maier  

                            Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy

16:30 – 16:40  General Discussion                             

16:40 – 17:40  Oral Communications

16:40 – 16:55           OC13

                                       Hypomagnesaemia in patients with cardiovascular disease and morbid obesity exacerbates dyslipidaemia and inflammatory syndrome

                                       Ioan A. Gutiu

                                   Department of Medical Emergencies,“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

16:55 – 17:10             OC14

                                       Magnesium supplementation improves metabolic syndrome parameters

                                      Kseniia Afitska

                                      Protina Pharmazeutische GmbH, Ismaning, Germany

17:10 – 17:25  OC15

                              Utility of magnesium sulfate in the treatment of rapid atrial fibrillation in the emergency department: a systematic review and meta-analysis

                              Megan Hoffer

                            Department of Emergency Medicine, George Washington University
Washington, DC, USA

17:25 – 17:40   Award Nomination and Closing Ceremony

Chairmen:        Andrzej Mazur (Clermont-Ferrand, France)

                               Rhian Touyz (Glasgow, UK – Montreal, Canada)

                               Federica I Wolf (Rome, Italy)