Glasgow local time
09:00 – 09:15 Connection
09:15 – 09:30 Welcome Remarks
Rhian Touyz (Glasgow, UK – Montreal, Canada)
Federica I Wolf (Rome, Italy)
09.30 – 11:40 SESSION 1 Magnesium: Environment, Nutrition and Health
Chairmen: Andrzej Mazur (Clermont-Ferrand, France)
Rhian Touyz (Glasgow, UK – Montreal, Canada)
09:30 – 09:50 Hypomagnesaemia: biomarker, relevance, clinical implications
Andrea Rosanoff
CMER Center for Magnesium Education and Research, Pahoa, USA
09:50 – 10:10 Magnesium in soil and consequences in the food chain
Roberta Cazzola
Department of Biomedical and Clinical Sciences, University of Milano, Italy
10:10 – 10:30 Magnesium: one of the building block of life
Stefano Iotti
Department of Pharmacy and Biotechnology, University of Bologna, Italy
10:30 – 10:45 Coffee / Tea Break
10:45 – 11:05 Cyclin M4 silencing and magnesium accumulation in NASH
Maria Luz Martinez-Chantar
Laboratory of Head, Liver Disease, Spanish Carlos III Health Institute, Derio, Spain
11:05 – 11:25 Magnesium and Thiamine in Alcohol Withdrawal Syndrome
Donogh Maguire
Glasgow Royal Infirmary, University of Glasgow, UK
11:25 – 11:40 General Discussion
11:40 – 12:25 Oral Communications
11:40 – 11:55 OC01
Mg quantification and distribution as potential biomarkers in Colorectal Cancer
Agnese Razzoli
Department of Transfusion Medicine, University of Reggio Emilia, Italy
11:55 – 12:10 OC02
Magnesium alleviates moderate stress in fibromyalgia
Nicolas Macian
Department of Clinical Investigation, INSERM Clermont-Ferrand, France
12:10 – 12:25 OC03
Decreased ionized magnesium and an increased ionized calcium/magnesium ratio in elderly hypertensives — relationship to artheriosclerosis
Klaus Kisters
Department of Med. Klinik, St. Anna Hospital & ESH Excellence Centre, Herne, Ruhr University Bochum, Germany
12:25 – 13:30 Lunch Break
13:30 – 13:50 Keynote Lecture
Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism
Muniswamy Madesh
Department of Medicine, University of Texas Health, San Antonio, USA
13:50 – 13:55 Discussion
13:55 – 14:15 Magnesium, immunity and infectious diseases an updated overview
Michael Lenardo
Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Besthesda, USA
14:15 – 14:20 Discussion
14:20 – 16:00 SESSION 2 Magnesium through the lifespan
Chairmen: Ka Kahe (New York, USA)
Federica I Wolf (Roma, Italy)
14:20 – 14:40 Mg and development
Loren Runnels
Department of Pharmacology Rutgers, Robert Wood Johnson Medical School
Piscataway, NJ, USA
14:40 – 15:00 Mg and aging
Ligia Dominguez
Department of Medicine and Surgery, Kore University of Enna, Italy
15:00 – 15:20 Magnesium and Progeria
Ricardo Villa-Bellosta
Department of Biochemistry and Molecular Biology, University of Santiago de Compostela, Spain
15:20 – 15:40 Magnesium, an invisible deficiency that could be harming your muscle health
Sara Castiglioni
Department of Clinical and Biomedical Sciences “Luigi Sacco”, University of Milano, Italy
15:40 – 15:50 General discussion
15:50 – 16:00 Coffee / Tea Break
16:00 – 16:45 Oral Communications
16:00 – 16:15 OC04
Can a Qualified Health Claim for Magnesium and High Blood Pressure Advance Public Health?
Rebecca Costello and Andrea Rosanoff
CMER Center for Magnesium Education and Research, Pahoa, USA
16:15 – 16:30 OC05
Fluorescent Indicators for Detection of Cellular Mg2+ with High Selectivity
Daniela Buccella
Department of Chemistry, New York University, New York, USA
16:30 – 16:45 OC06
Magnesium effect on the cardiovascular-muscle-bone triad
Marie-Eva Pickering
Department of Rheumatology, University Hospital Clermont-Ferrand, France
16:45 – 17:00 OC07
Lactobacillus fermentum supplementation normalizes magnesium fecal excretion and delays and reduces high blood pressure and Na, Na/K ATPase activities in salt dependent hypertension
Ruben Biomon
Department of Biophysics and Biochemistry, Venezuelan Institute of Scientific Research, Miranda State, Venezuela
Friday, June 24th
09:00 – 11:00 SESSION 3
Molecular Mechanisms of Magnesium Homeostasis
Chairmen: Francisco Rios (Glasgow, UK) Jeroen de Baaji (Nijmegen, The Netherlands)
09:00 – 09:20 The molecular appearance and regulatory mechanisms of TRPM7 channel complexes
Vladimir Chubanov
Department of Pharmacology and Toxicology, Walther-Straub Institute, LMU Munich, Germany
09:20 – 09:40 Genetic and drug-induced hypomagnesemia: different cause, same mechanism
Jeroen De Baaij
Department of Molecular Life Sciences, Radboud Institute, Nijmegen, the Netherlands
09:40 – 10:00 Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
Cristina Manatschal
Department of Biochemistry, University of Zurich, Switzerland
10:00 – 10:10 Coffee / Tea Break
10:10 – 10:30 Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis
Francisco Rios
Department of Cardiovascular and Medical Sciences, University of Glasgow, UK
10:30 – 10:50 Severe magnesium wasting in Kenny Caffey Syndrome- searching for molecular causes
Heidi Schigt
Department of Molecular Life Sciences, Radboud Institute, Nijmegen, the Netherlands
Francisco Rios
Department of Cardiovascular and Medical Sciences, University of Glasgow, UK
10:50 – 11:00 General Discussion
11:00 – 12:00 Oral Communications
11:00 – 11:15 OC08
Palmitoylation regulates cellular distribution of and transmembrane Calcium flux through TrpM7
Xing GAO
Department of Cardiovascular & Medical Sciences, University of Glasgow, UK
11:15 – 11:30 OC09
TRPM7 Modulates Human Pancreatic Stellate Cell Activation
Julie Auwercx
Department of Sciences, University of Picardie Jules Verne, Amiens, France
11:30 – 11:45 OC10
TRPM7 channel-kinase, magnesium and pH in immune cells
Ashot Kozak
Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine, Wright State University, Dayton, USA
11:45 – 12:00 OC11
TRPM7 kinase mediates hypomagnesemia-associated seizure and death
Samuel Dudley
Department of Medicine, Division of Cardiology, the Lillehei Heart Institute, University of Minnesota at Twin Cities, Minneapolis, USA
12:00 – 13:00 Lunch Break
13:00 – 15:00 SESSION 4
Magnesium in communicable disease
Chairmen: Federica I Wolf (Roma, Italy)
Jeanette AM Maier (Milano, Italy)
13:00 – 13:20 How Pathogens Feel and Overcome Magnesium Limitation
Eduardo A. Groisman
Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, USA
13:20 – 13:40 Counteract bacterial infections: factor SLC11A1 restricts Salmonella growth through magnesium deprivation
Olivier Cunrath
Department of Metals and Microorganisms, University of Strasbourg, Illkirch, France
13:40 – 14:00 Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation
Asparouh Iliev
Department of Molecular Neuroinfectiology, University of Bern, Switzerland
14:00 – 14:20 The PRL-2:CNNM protein complex and magnesium interaction in the modulation of adenoviral infection
Michel L. Tremblay
Department of Biochemistry and Goodman Cancer Institute. McGill University, Montreal, Canada
14:20 – 14:40 Mg in Sars-Cov-2
Fernando Guerrero-Romero
Biomedical Research Unit of the Mexican Social Security Institute at Durango, Research Group on Diabetes and Chronic Illnesses at Durango, Mexico
14:40 – 15:00 Increased Mortality Associated with Hypermagnesemia in Severe COVID-19 Illness
Jacob Stevens
Department of Nephrology, Columbia University Irving Medical Center New York, USA
15:00 – 15:10 General Discussion
15:10 – 15:25 Oral Communication
OC12
Use of Magnesium for Preventing Cardiac Damages by SARS-CoV-2
Jin O-Uchi
Department of Medicine University of Minnesota, USA
15:25 – 15:30 Coffee / Tea Break
15:30 – 16:40 SESSION 5
Magnesium in noncommunicable diseases
Chairmen: Oliver Micke (Bielefeld, Germany)
Rhian Touyz (Glasgow, UK – Montreal, Canada)
15:30 – 15:50 Serum magnesium concentration and incident cognitive impairment: findings from the REGARDS study
Ka Kahe
Columbia University Irving Medical Center, New York, USA
15:50 – 16:10 Magnesium in oncology an update
Oliver Micke
Department of Radiotherapy and Radiation Oncology, Franziskus Hospital
Bielefeld, Germany
16:10 – 16:30 News on Magnesium and the Vascular system
Jeanette AM Maier
Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy
16:30 – 16:40 General Discussion
16:40 – 17:40 Oral Communications
16:40 – 16:55 OC13
Hypomagnesaemia in patients with cardiovascular disease and morbid obesity exacerbates dyslipidaemia and inflammatory syndrome
Ioan A. Gutiu
Department of Medical Emergencies,“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
16:55 – 17:10 OC14
Magnesium supplementation improves metabolic syndrome parameters
Kseniia Afitska
Protina Pharmazeutische GmbH, Ismaning, Germany
17:10 – 17:25 OC15
Utility of magnesium sulfate in the treatment of rapid atrial fibrillation in the emergency department: a systematic review and meta-analysis
Megan Hoffer
Department of Emergency Medicine, George Washington University
Washington, DC, USA
17:25 – 17:40 Award Nomination and Closing Ceremony
Chairmen: Andrzej Mazur (Clermont-Ferrand, France)
Rhian Touyz (Glasgow, UK – Montreal, Canada)
Federica I Wolf (Rome, Italy)